NHERF1 Between Promises and Hopes: Overview on Cancer and Prospective Openings

Na+/H+ exchanger regulatory factor 1 (NHERF1) is a scaffold protein, with two tandem PDZ domains and a carboxyl-terminal ezrin-binding (EB) region. This particular sticky structure is responsible for its interaction with different molecules to form multi-complexes that have a pivotal role in a lot o...

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Bibliographic Details
Main Authors: Matteo Centonze, Concetta Saponaro, Anita Mangia
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317304722