Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells

Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells

Chronic myeloid leukemia stem cells (CML LSCs) are a rare and quiescent population that are resistant to tyrosine kinase inhibitors (TKI). When TKI therapy is discontinued in CML patients in deep, sustained and apparently stable molecular remission, these cells in approximately half of the cases res...

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Bibliographic Details
Main Authors: Mohammad Houshmand, Alireza Kazemi, Ali Anjam Najmedini, Muhammad Shahzad Ali, Valentina Gaidano, Alessandro Cignetti, Carmen Fava, Daniela Cilloni, Giuseppe Saglio, Paola Circosta
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Journal of Clinical Medicine
Subjects:
chronic myeloid leukemia
leukemia stem cells
bone marrow microenvironment
treatment free remission
Online Access:https://www.mdpi.com/2077-0383/10/24/5805

Internet

https://www.mdpi.com/2077-0383/10/24/5805

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