Polygenic risk scores for cardiovascular diseases and type 2 diabetes

Polygenic risk scores (PRSs) are a promising approach to accurately predict an individual’s risk of developing disease. The area under the receiver operating characteristic curve (AUC) of PRSs in their population are often only reported for models that are adjusted for age and sex, which are known r...

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Bibliographic Details
Main Authors: Chi Kuen Wong, Enes Makalic, Gillian S. Dite, Lawrence Whiting, Nicholas M. Murphy, John L. Hopper, Richard Allman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9718402/?tool=EBI