The protective capability of Hedyotis diffusa Willd on lupus nephritis by attenuating the IL-17 expression in MRL/lpr mice

The protective capability of Hedyotis diffusa Willd on lupus nephritis by attenuating the IL-17 expression in MRL/lpr mice

Lupus nephritis (LN), the most severe organ manifestation of systemic lupus erythematosus (SLE), is generally treated with glucocorticoids (GC) in clinical practice, leading to drug resistance and adverse effects in the long term. Fortunately, the combination of GC and traditional Chinese medical pr...

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Bibliographic Details
Main Authors: Ying Li, Tao Ding, Jing Chen, Jinjun Ji, Weijie Wang, Bin Ding, Weihong Ge, Yongsheng Fan, Li Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
Hedyotis diffusa Willd
lupus nephritis
network pharmacology
interleukin-17
STAT3
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.943827/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.943827/full

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