Penostatin Derivatives, a Novel Kind of Protein Phosphatase 1B Inhibitors Isolated from Solid Cultures of the Entomogenous Fungus Isaria tenuipes

Penostatin Derivatives, a Novel Kind of Protein Phosphatase 1B Inhibitors Isolated from Solid Cultures of the Entomogenous Fungus Isaria tenuipes

Protein tyrosine phosphatase 1B (PTP1B) is implicated as a negative regulator of insulin receptor (IR) signaling and a potential drug target for the treatment of type II diabetes and other associated metabolic syndromes. Therefore, small molecular inhibitors of PTP1B can be considered as an attracti...

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Bibliographic Details
Main Authors: Yu-Peng Chen, Chun-Gui Yang, Pei-Yao Wei, Lin Li, Du-Qiang Luo, Zhi-Hui Zheng, Xin-Hua Lu
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Molecules
Subjects:
Isaria tenuipes
penostatin derivatives
protein phosphatase 1B inhibitor
Online Access:http://www.mdpi.com/1420-3049/19/2/1663

Internet

http://www.mdpi.com/1420-3049/19/2/1663

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