A Method to Monitor the NAD<sup>+</sup> Metabolome—From Mechanistic to Clinical Applications
Nicotinamide adenine dinucleotide (NAD<sup>+</sup>) and its reduced form (NADH) are coenzymes employed in hundreds of metabolic reactions. NAD<sup>+</sup> also serves as a substrate for enzymes such as sirtuins, poly(ADP-ribose) polymerases (PARPs) and ADP-ribosyl cyclases. G...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/19/10598 |