<i>Dictyostelium</i> Differentiation-Inducing Factor 1 Promotes Glucose Uptake via Direct Inhibition of Mitochondrial Malate Dehydrogenase in Mouse 3T3-L1 Cells

<i>Dictyostelium</i> Differentiation-Inducing Factor 1 Promotes Glucose Uptake via Direct Inhibition of Mitochondrial Malate Dehydrogenase in Mouse 3T3-L1 Cells

Differentiation-inducing factor 1 (DIF-1), found in <i>Dictyostelium discoideum</i>, has antiproliferative and glucose-uptake-promoting activities in mammalian cells. DIF-1 is a potential lead for the development of antitumor and/or antiobesity/antidiabetes drugs, but the mechanisms unde...

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Bibliographic Details
Main Authors: Yuzuru Kubohara, Yuko Fukunaga, Ayako Shigenaga, Haruhisa Kikuchi
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Dictyostelium discoideum</i>
DIF-1
obesity
diabetes
MDH2
AMPK
Online Access:https://www.mdpi.com/1422-0067/25/3/1889

Internet

https://www.mdpi.com/1422-0067/25/3/1889

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