Crosstalk between arginine, glutamine, and the branched chain amino acid metabolism in the tumor microenvironment

Arginine, glutamine, and the branched chain amino acids (BCAAs) are a focus of increased interest in the field of oncology due to their importance in the metabolic reprogramming of cancer cells. In the tumor microenvironment (TME), these amino acids serve to support the elevated biosynthetic and ene...

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Bibliographic Details
Main Authors: Tanner J. Wetzel, Sheila C. Erfan, Lucas D. Figueroa, Leighton M. Wheeler, Elitsa A. Ananieva
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1186539/full