Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates

<b>AL-471</b>, the leading exponent of a class of potent HIV and enterovirus A71 (EV-A71) entry inhibitors discovered in our research group, contains four <span style="font-variant: small-caps;">l</span>-tryptophan (Trp) units bearing an aromatic isophthalic acid di...

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Bibliographic Details
Main Authors: Olaia Martí-Marí, Rana Abdelnabi, Dominique Schols, Johan Neyts, María-José Camarasa, Federico Gago, Ana San-Félix
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/4/3539