Changes to the mtDNA copy number during yeast culture growth

We show that the mitochondrial DNA (mtDNA) copy number in growing cultures of the yeast Saccharomyces cerevisiae increases by a factor of up to 4, being lowest (approx. 10 per haploid genome) and stable during rapid fermentative growth, and highest at the end of the respiratory phase. When yeast are...

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Bibliographic Details
Main Authors: Ben Galeota-Sprung, Amy Fernandez, Paul Sniegowski
Format: Article
Language:English
Published: The Royal Society 2022-07-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.211842