Crystal structure of Oryza sativa TDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis

Crystal structure of Oryza sativa TDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis

Plant tryptophan decarboxylase (TDC) is a type II Pyridoxal-5′-phosphate-dependent decarboxylase (PLP_DC) that could be used as a target to genetically improve crops. However, lack of accurate structural information on plant TDC hampers the understanding of its decarboxylation mechanisms. In the pre...

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Bibliographic Details
Main Authors: Yuanze Zhou, Lijing Liao, Xikai Liu, Biao Liu, Xinxin Chen, Yan Guo, Chuanlong Huang, Yucheng Zhao, Zhixiong Zeng
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Journal of Advanced Research
Subjects:
Crystal structure
Tryptophan decarboxylase
Melatonin biosynthesis
Substrate specificity
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220301132

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http://www.sciencedirect.com/science/article/pii/S2090123220301132

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