MTOR Signaling and Metabolism in Early T Cell Development

The mechanistic target of rapamycin (mTOR) controls cell fate and responses via its functions in regulating metabolism. Its role in controlling immunity was unraveled by early studies on the immunosuppressive properties of rapamycin. Recent studies have provided insights on how metabolic reprogrammi...

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Bibliographic Details
Main Authors: Guy Werlen, Ritika Jain, Estela Jacinto
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/5/728