Cross-tissue correlations of genome-wide DNA methylation in Japanese live human brain and blood, saliva, and buccal epithelial tissues

Abstract Neuroepigenetics considers genetic sequences and the interplay with environmental influences to elucidate vulnerability risk for various neurological and psychiatric disorders. However, evaluating DNA methylation of brain tissue is challenging owing to the issue of tissue specificity. Conse...

Full description

Bibliographic Details
Main Authors: Shota Nishitani, Makoto Isozaki, Akiko Yao, Yoshifumi Higashino, Takahiro Yamauchi, Masamune Kidoguchi, Satoshi Kawajiri, Kenzo Tsunetoshi, Hiroyuki Neish, Hirochika Imoto, Hidetaka Arishima, Toshiaki Kodera, Takashi X. Fujisawa, Sadahiro Nomura, Kenichiro Kikuta, Gen Shinozaki, Akemi Tomoda
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02370-0