Combined metabolomics and transcriptomics analysis of rats under neuropathic pain and pain-related depression

Neuropathic pain often leads to negative emotions, which in turn can enhance the sensation of pain. This study aimed to investigate the molecular mechanisms mediating neuropathic pain and negative emotions. Chronic constriction injury (CCI) rats were used as model animals and behavioral tests were c...

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Bibliographic Details
Main Authors: Caiyun Xi, Liqiong He, Zhifeng Huang, Jianxi Zhang, Kailu Zou, Qulian Guo, Changsheng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1320419/full