Extremely low-coverage whole genome sequencing in South Asians captures population genomics information

Extremely low-coverage whole genome sequencing in South Asians captures population genomics information

Abstract Background The cost of Whole Genome Sequencing (WGS) has decreased tremendously in recent years due to advances in next-generation sequencing technologies. Nevertheless, the cost of carrying out large-scale cohort studies using WGS is still daunting. Past simulation studies with coverage at...

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Bibliographic Details
Main Authors: Navin Rustagi, Anbo Zhou, W. Scott Watkins, Erika Gedvilaite, Shuoguo Wang, Naveen Ramesh, Donna Muzny, Richard A. Gibbs, Lynn B. Jorde, Fuli Yu, Jinchuan Xing
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
Single nucleotide variant
Whole genome sequencing
South Asian
Extremely low coverage
Population structure
Imputation
Online Access:http://link.springer.com/article/10.1186/s12864-017-3767-6

Internet

http://link.springer.com/article/10.1186/s12864-017-3767-6

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