Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo

Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo

Abstract Background Single low-dose primaquine (SLDPQ) effectively blocks the transmission of Plasmodium falciparum malaria, but anxiety remains regarding its haemolytic potential in patients with glucose-6-phopshate dehydrogenase (G6PD) deficiency. We, therefore, examined the independent effects of...

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Bibliographic Details
Main Authors: Marie A. Onyamboko, Peter Olupot-Olupot, Winifred Were, Cate Namayanja, Peter Onyas, Harriet Titin, Joy Baseke, Rita Muhindo, Daddy K. Kayembe, Pauline O. Ndjowo, Benjamin B. Basara, Charles B. Okalebo, Thomas N. Williams, Sophie Uyoga, Chiraporn Taya, Adeola Bamisaiye, Caterina Fanello, Kathryn Maitland, Nicholas P. J. Day, Walter R. J. Taylor, Mavuto Mukaka
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Medicine
Subjects:
Primaquine
Plasmodium falciparum
Haemoglobin
Glucose-6-phosphate dehydrogenase deficiency
Anaemia
Children
Online Access:https://doi.org/10.1186/s12916-023-03105-0

Internet

https://doi.org/10.1186/s12916-023-03105-0

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