Identification of the visceral pain pathway activated by noxious colorectal distension in mice

In patients with irritable bowel syndrome (IBS), visceral pain is evoked more readily following distension of the colorectum. However, the identity of extrinsic afferent nerve pathway that detects and transmits visceral pain from the colorectum to the spinal cord is unclear. In this study, we identi...

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Bibliographic Details
Main Authors: Melinda eKyloh, Sarah eNicholas, Vladimir P Zagorodnyuk, Simon J. H Brookes, Nick J Spencer
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2011.00016/full