Target mRNA abundance dilutes microRNA and siRNA activity
Abstract Post‐transcriptional regulation by microRNAs and siRNAs depends not only on characteristics of individual binding sites in target mRNA molecules, but also on system‐level properties such as overall molecular concentrations. We hypothesize that an intracellular pool of microRNAs/siRNAs faced...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2010-04-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/msb.2010.24 |