Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth.

Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth.

Broadly neutralizing antibodies (bNAbs) are rarely elicited by current human immunodeficiency virus type 1 (HIV-1) vaccine designs, but the presence of bNAbs in naturally infected individuals may be associated with high plasma viral loads, suggesting that the magnitude, duration, and diversity of vi...

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Bibliographic Details
Main Authors: Valentine U Chukwuma, Nurgun Kose, D Noah Sather, Gopal Sapparapu, Rachel Falk, Hannah King, Vidisha Singh, Rebecca Lampley, Delphine C Malherbe, Noah T Ditto, Jonathan T Sullivan, Trevor Barnes, Benjamin J Doranz, Celia C Labranche, David C Montefiori, Spyros A Kalams, Nancy L Haigwood, James E Crowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209437

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https://doi.org/10.1371/journal.pone.0209437

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