Diagnostic strategy of metagenomic next-generation sequencing for gram negative bacteria in respiratory infections

Diagnostic strategy of metagenomic next-generation sequencing for gram negative bacteria in respiratory infections

Abstract Objective This study aims to identify the most effective diagnostic method for distinguishing pathogenic and non-pathogenic Gram-negative bacteria (GNB) in suspected pneumonia cases using metagenomic next-generation sequencing (mNGS) on bronchoalveolar lavage fluid (BALF) samples. Methods T...

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Bibliographic Details
Main Authors: Wenyan Liang, Qun Zhang, Qian Qian, Mingyue Wang, Yuchen Ding, Ji Zhou, Yi Zhu, Yu Jin, Xuesong Chen, Hui Kong, Wei Song, Xin Lu, Xiaodong Wu, Xiaoyong Xu, Shanling Dai, Wenkui Sun
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Metagenomic next-generation sequencing
Gram-negative bacteria
Interpretational approaches
Diagnostic accuracy
Online Access:https://doi.org/10.1186/s12941-024-00670-x

Internet

https://doi.org/10.1186/s12941-024-00670-x

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