Directed evolution of a neutrophilic and mesophilic methanol dehydrogenase based on high-throughput and accurate measurement of formaldehyde

Directed evolution of a neutrophilic and mesophilic methanol dehydrogenase based on high-throughput and accurate measurement of formaldehyde

Methanol is a promising one-carbon feedstock for biomanufacturing, which can be sustainably produced from carbon dioxide and natural gas. However, the efficiency of methanol bioconversion is limited by the poor catalytic properties of nicotinamide adenine dinucleotide (NAD+)-dependent methanol dehyd...

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Bibliographic Details
Main Authors: Jin Qian, Liwen Fan, Jinxing Yang, Jinhui Feng, Ning Gao, Guimin Cheng, Wei Pu, Wenjuan Zhou, Tao Cai, Shuang Li, Ping Zheng, Jibin Sun, Depei Wang, Yu Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Synthetic and Systems Biotechnology
Subjects:
Methanol dehydrogenase
Formaldehyde biosensor
Directed evolution
C1 bioconversion
Methanol oxidation
Methylotrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X23000340

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http://www.sciencedirect.com/science/article/pii/S2405805X23000340

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