Regulation of APD and Force by the Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

Regulation of APD and Force by the Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

The physiological importance of NCX in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is not well characterized but may depend on the relative strength of the current, compared to adult cardiomyocytes, and on the exact spatial arrangement of proteins involved in Ca<sup>...

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Bibliographic Details
Main Authors: Djemail Ismaili, Katrin Gurr, András Horváth, Lei Yuan, Marc D. Lemoine, Carl Schulz, Jascha Sani, Johannes Petersen, Hermann Reichenspurner, Paulus Kirchhof, Thomas Jespersen, Thomas Eschenhagen, Arne Hansen, Jussi T. Koivumäki, Torsten Christ
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
hiPSC-CM
human ventricular cardiomyocytes
rat ventricular cardiomyocytes
NCX
APD
force
Online Access:https://www.mdpi.com/2073-4409/11/15/2424

Internet

https://www.mdpi.com/2073-4409/11/15/2424

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