Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number.

<h4>Background</h4>We have previously identified genome-wide DNA methylation changes in a cell line model of breast cancer metastasis. These complex epigenetic changes that we observed, along with concurrent karyotype analyses, have led us to hypothesize that complex genomic alterations...

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Bibliographic Details
Main Authors: Joseph Andrews, Wendy Kennette, Jenna Pilon, Alexandra Hodgson, Alan B Tuck, Ann F Chambers, David I Rodenhiser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20084286/?tool=EBI