Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway

Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway

The goal of the study was to analyze whether WJP can alleviate visceral hypersensitivity in IBS-D model rats. In this study, 36 Sprague–Dawley (SD) rats aged 4 weeks old were randomly divided into two groups: the model group (n = 27) and the control group (n = 9). The rat model of IBS-D was establis...

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Bibliographic Details
Main Authors: Tianyuan Jiang, Ran Niu, Qian Liu, Yuhan Fu, Xiaoying Luo, Tao Zhang, Baoqi Wu, Juan Han, Yang Yang, Xiaolan Su, Jiande D. Z. Chen, Gengqing Song, Wei Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
rat model of IBS-D
visceral hypersensitivity
Chinese herbal medicine
colon
hippocampus
MEK/ERK signal pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.955421/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.955421/full

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