Morita–Baylis–Hillman reaction of acrylamide with isatin derivatives

The Morita–Baylis–Hillman reaction of acrylamide, as an activated alkene, has seen little development due to its low reactivity. We have developed the reaction using isatin derivatives with acrylamide, DABCO as a promoter and phenol as an additive in acetonitrile. The corresponding aza version with...

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Bibliographic Details
Main Authors: Radhey M. Singh, Kishor Chandra Bharadwaj, Dharmendra Kumar Tiwari
Format: Article
Language:English
Published: Beilstein-Institut 2014-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.10.315