Effect of the p38 MAPK inhibitor doramapimod on the systemic inflammatory response to intravenous lipopolysaccharide in horses

Abstract Background Doramapimod, a p38 MAPK inhibitor, is a potent anti‐inflammatory drug that decreases inflammatory cytokine production in equine whole blood in vitro. It may have benefits for treating systemic inflammation in horses. Objective To determine whether doramapimod is well tolerated wh...

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Bibliographic Details
Main Authors: Jennifer Bauquier, Elizabeth Tudor, Simon Bailey
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Journal of Veterinary Internal Medicine
Subjects:
Online Access:https://doi.org/10.1111/jvim.15847