Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon

Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon

Ribosomes stall on truncated or otherwise damaged mRNAs. Bacteria rely on ribosome rescue mechanisms to replenish the pool of ribosomes available for translation. Trans-translation, the main ribosome-rescue pathway, uses a circular hybrid transfer-messenger RNA (tmRNA) to restart translation and lab...

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Bibliographic Details
Main Authors: David Teran, Ying Zhang, Andrei A. Korostelev
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Microbiology
Subjects:
endogenous tmRNA
tmRNA decoding
A-minor interactions
SmpB
cryo-EM
alanyl-tRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1369760/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1369760/full

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