Hyaluronidase treatment of synovial fluid is required for accurate detection of inflammatory cells and soluble mediators

Hyaluronidase treatment of synovial fluid is required for accurate detection of inflammatory cells and soluble mediators

Abstract Background Synovial fluid (SF) is commonly used for diagnostic and research purposes, as it is believed to reflect the local inflammatory environment. Owing to its complex composition and especially the presence of hyaluronic acid, SF is usually viscous and non-homogeneous. In this study, w...

Full description

Bibliographic Details
Main Authors: Hilde Brouwers, Johannes Hendrick von Hegedus, Enrike van der Linden, Rachid Mahdad, Margreet Kloppenburg, René Toes, Martin Giera, Andreea Ioan-Facsinay
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Arthritis Research & Therapy
Subjects:
Synovial fluid
Hyaluronidase
Rheumatoid arthritis
Online Access:https://doi.org/10.1186/s13075-021-02696-4

Internet

https://doi.org/10.1186/s13075-021-02696-4

Similar Items