A cautionary tale: an evaluation of the performance of treatment switching adjustment methods in a real world case study

Abstract Background Treatment switching in randomised controlled trials (RCTs) is a problem for health technology assessment when substantial proportions of patients switch onto effective treatments that would not be available in standard clinical practice. Often statistical methods are used to adju...

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Bibliographic Details
Main Authors: Nicholas R Latimer, Alice Dewdney, Marco Campioni
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-024-02140-6