A cautionary tale: an evaluation of the performance of treatment switching adjustment methods in a real world case study
Abstract Background Treatment switching in randomised controlled trials (RCTs) is a problem for health technology assessment when substantial proportions of patients switch onto effective treatments that would not be available in standard clinical practice. Often statistical methods are used to adju...
Main Authors: | Nicholas R Latimer, Alice Dewdney, Marco Campioni |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
|
Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-024-02140-6 |
Similar Items
-
Two-stage estimation to adjust for treatment switching in randomised trials: a simulation study investigating the use of inverse probability weighting instead of re-censoring
by: N. R. Latimer, et al.
Published: (2019-03-01) -
Comparison of Survival Outcomes of Different Treatment Options for cT1-2, N0 Glottic Carcinoma: A Propensity Score–Weighted Analysis
by: Qi-wei Liang, et al.
Published: (2022-05-01) -
The Association Between Congestive Heart Failure and One-Year Mortality After Surgery in Singaporean Adults: A Secondary Retrospective Cohort Study Using Propensity-Score Matching, Propensity Adjustment, and Propensity-Based Weighting
by: Yong Han, et al.
Published: (2022-06-01) -
Power and sample sizes estimation in clinical trials with treatment switching in intention-to-treat analysis: a simulation study
by: Lejun Deng, et al.
Published: (2023-02-01) -
Effectiveness of remdesivir in hospitalized nonsevere patients with COVID-19 in Japan: A large observational study using the COVID-19 Registry Japan
by: Shinya Tsuzuki, et al.
Published: (2022-05-01)