Neutrophil Gelatinase-Associated Lipocalin (NGAL), Pro-Matrix Metalloproteinase-9 (pro-MMP-9) and Their Complex Pro-MMP-9/NGAL in Leukaemias

Neutrophil Gelatinase-Associated Lipocalin (NGAL), Pro-Matrix Metalloproteinase-9 (pro-MMP-9) and Their Complex Pro-MMP-9/NGAL in Leukaemias

Matrix metalloproteinase (MMP)-9 and neutrophil gelatinase-associated lipocalin (NGAL) have gained attention as cancer biomarkers. The inactive zymogen form of MMP-9 (pro-MMP-9) also exists as a disulphide-linked heterodimer bound to NGAL in humans. Leukaemias represent a heterogeneous group of neop...

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Bibliographic Details
Main Authors: Sandrine Bouchet, Brigitte Bauvois
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Cancers
Subjects:
hematologic malignancy
gelatinase
cancer, signalling
cell surface binding
Online Access:http://www.mdpi.com/2072-6694/6/2/796

Internet

http://www.mdpi.com/2072-6694/6/2/796

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