Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme.

Flaviviruses are small, capped positive sense RNA viruses that replicate in the cytoplasm of infected cells. Dengue virus and other related flaviviruses have evolved RNA capping enzymes to form the viral RNA cap structure that protects the viral genome and directs efficient viral polyprotein transla...

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Bibliographic Details
Main Authors: Brittney R Henderson, Bejan J Saeedi, Grace Campagnola, Brian J Geiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192115?pdf=render