Identification of a disulfide bridge important for transport function of SNAT4 neutral amino acid transporter.

SNAT4 is a member of system N/A amino acid transport family that primarily expresses in liver and muscles and mediates the transport of L-alanine. However, little is known about the structure and function of the SNAT family of transporters. In this study, we showed a dose-dependent inhibition in tra...

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Bibliographic Details
Main Authors: Rugmani Padmanabhan Iyer, Sumin Gu, Bruce J Nicholson, Jean X Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579933?pdf=render