Tetramethylpyrazine inhibits NETs formation induced by high glucose by regulating NRF2/HO-1 pathway

Objective To investigate the effect and mechanism of tetramethylpyrazine (TMP) on the formation of neutrophil extracellular traps (NETs) induced by high glucose. Methods The viability of neutrophils treated with TMP of 0, 5, 10, 20, 40, and 80 μmol/L for 4 h was measured by CCK-8 assay. Neutrophils...

Full description

Bibliographic Details
Main Authors: CHEN Jinquan, ZHAO Long, DING Xuanheng, WANG Lingda, WEN Yan
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2022-11-01
Series:陆军军医大学学报
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202204038.htm