High-fidelity (repeat) consensus sequences from short reads using combined read clustering and assembly

Abstract Background Despite the many cheap and fast ways to generate genomic data, good and exact genome assembly is still a problem, with especially the repeats being vastly underrepresented and often misassembled. As short reads in low coverage are already sufficient to represent the repeat landsc...

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Bibliographic Details
Main Authors: Ludwig Mann, Kristin Balasch, Nicola Schmidt, Tony Heitkam
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09948-4