Intermittent Hypoxic Therapy Inhibits Allogenic Bone-Graft Resorption by Inhibition of Osteoclastogenesis in a Mouse Model

Intermittent Hypoxic Therapy Inhibits Allogenic Bone-Graft Resorption by Inhibition of Osteoclastogenesis in a Mouse Model

Systemic Intermittent Hypoxic Therapy (IHT) relies on the adaptive response to hypoxic stress. We investigated allogenic bone-graft resorption in the lumbar spine in 48 mice. The mice were exposed to IHT for 1 week before surgery or 1 week after surgery and compared with controls after 1 and 4 weeks...

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Bibliographic Details
Main Authors: Natasja Leth Bergholt, Ari Demirel, Michael Pedersen, Ming Ding, Tue Wenzel Kragstrup, Thomas Andersen, Bent Winding Deleuran, Casper Bindzus Foldager
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
intermittent hypoxic therapy
bone
spine
Online Access:https://www.mdpi.com/1422-0067/23/1/323

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https://www.mdpi.com/1422-0067/23/1/323

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