Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice

Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice

Combined antiretroviral therapy ushered an era of survivable HIV infection in which people living with HIV (PLH) conduct normal life activities and enjoy measurably extended lifespans. However, despite viral control, PLH often experience a variety of cognitive, emotional, and physical phenotypes tha...

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Bibliographic Details
Main Authors: Benjamin J. Bell, Kristen R. Hollinger, Pragney Deme, Shinji Sakamoto, Yuto Hasegawa, David Volsky, Atsushi Kamiya, Norman Haughey, Xiaolei Zhu, Barbara S. Slusher
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
EcoHIV-infected mice
Psychosocial deficits
Sleep deficits
Microglial immune genes
Glutamine antagonist
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354622000680

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http://www.sciencedirect.com/science/article/pii/S2666354622000680

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