Comparing the epidermal growth factor interaction with four different cell lines: intriguing effects imply strong dependency of cellular context.

The interaction of the epidermal growth factor (EGF) with its receptor (EGFR) is known to be complex, and the common over-expression of EGF receptor family members in a multitude of tumors makes it important to decipher this interaction and the following signaling pathways. We have investigated the...

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Bibliographic Details
Main Authors: Hanna Björkelund, Lars Gedda, Karl Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3031572?pdf=render