Homozygous A polymorphism of the complement <it>C1qA</it><sub><it>276</it></sub> correlates with prolonged overall survival in patients with diffuse large B cell lymphoma treated with R-CHOP

Homozygous A polymorphism of the complement <it>C1qA</it><sub><it>276</it></sub> correlates with prolonged overall survival in patients with diffuse large B cell lymphoma treated with R-CHOP

<p>Abstract</p> <p>Background</p> <p>The precise mechanism of action for rituximab (R) is not fully elucidated. Besides antibody-dependent cellular cytotoxicity (ADCC), complements may also play an important role in the clinical response to rituximab-based therapy in di...

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Bibliographic Details
Main Authors: Jin Xuan, Ding Huirong, Ding Ning, Fu Zhiying, Song Yuqin, Zhu Jun
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Hematology & Oncology
Subjects:
Complement
Polymorphism
Rituximab
DLBCL
C1qA
Online Access:http://www.jhoonline.org/content/5/1/51

Internet

http://www.jhoonline.org/content/5/1/51

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