Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

Cardiac arrhythmias are a major cause of morbidity and mortality. In younger patients, the majority of sudden cardiac deaths have an underlying Mendelian genetic cause. Over the last 15 years, enormous progress has been made in identifying the distinct clinical phenotypes and in studying the basic c...

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Bibliographic Details
Main Authors: Maaike eHoekstra, Christine L. Mummery, Arthur A.M. Wilde, Connie R. Bezzina, Arie O. Verkerk
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00346/full