GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites.

Efforts to control the global malaria health crisis are undermined by antimalarial resistance. Identifying mechanisms of resistance will uncover the underlying biology of the Plasmodium falciparum malaria parasites that allow evasion of our most promising therapeutics and may reveal new drug targets...

Full description

Bibliographic Details
Main Authors: Andrew J Jezewski, Ann M Guggisberg, Dana M Hodge, Naomi Ghebremichael, Gavin Nicholas John, Lisa K McLellan, Audrey Ragan Odom John
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010803