Search for specific biomarkers of IFNβ bioactivity in patients with multiple sclerosis.

Myxovirus A (MxA), a protein encoded by the MX1 gene with antiviral activity, has proven to be a sensitive measure of IFNβ bioactivity in multiple sclerosis (MS). However, the use of MxA as a biomarker of IFNβ bioactivity has been criticized for the lack of evidence of its role on disease pathogenes...

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Main Authors: Sunny Malhotra, Marta F Bustamante, Francisco Pérez-Miralles, Jordi Rio, Mari Carmen Ruiz de Villa, Esteban Vegas, Lara Nonell, Florian Deisenhammer, Nicolás Fissolo, Ramil N Nurtdinov, Xavier Montalban, Manuel Comabella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21886806/?tool=EBI