RNAi-reduced bladder TGF-β1 expression improves bladder function and fibrosis in rats with spinal cord injury

RNAi-reduced bladder TGF-β1 expression improves bladder function and fibrosis in rats with spinal cord injury

Objective To explore the effect of reducing bladder TGF-β1 expression with RNA interference(RNAi) on neurogenic bladder(NB). Methods Forty-eight female rats were evenly divided into sham, T10 transaction, LV-vector and LV-shTGF-β1 groups. The sham group underwent sham operation of T10 spinal cor...

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Bibliographic Details
Main Author: JIA Chun-song, ZHAO Yan-po, SHANG Zhen-hua, XING Tian-ying, OU Tong-wen
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-07-01
Series:Jichu yixue yu linchuang
Subjects:
spinal cord injury|detrusor over activity|bladder fibrosis|rna interference(rnai)|tgf-β1
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200962.pdf

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http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200962.pdf

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