Treatment for ovarian clear cell carcinoma with combined inhibition of WEE1 and ATR

Treatment for ovarian clear cell carcinoma with combined inhibition of WEE1 and ATR

Abstract Background Standard platinum-based therapy for ovarian cancer is inefficient against ovarian clear cell carcinoma (OCCC). OCCC is a distinct subtype of epithelial ovarian cancer. OCCC constitutes 25% of ovarian cancers in East Asia (Japan, Korea, China, Singapore) and 6–10% in Europe and No...

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Bibliographic Details
Main Authors: Wenwen Chien, Jeffrey W. Tyner, Sigal Gery, Yueyuan Zheng, Li-Yan Li, Mohan Shankar Gopinatha Pillai, Chehyun Nam, Neil A. Bhowmick, De-Chen Lin, H. Phillip Koeffler
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Ovarian Research
Subjects:
Ovarian clear cell carcinoma
ATR
WEE1
Online Access:https://doi.org/10.1186/s13048-023-01160-y

Internet

https://doi.org/10.1186/s13048-023-01160-y

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