Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders.

Formyl peptide receptors (FPR) belong to a family of sensors of the immune system that detect microbe-associated molecules and inform various cellular and sensorial mechanisms to the presence of pathogens in the host. Here we demonstrate that Fpr2/3-deficient mice show a distinct profile of behaviou...

Full description

Bibliographic Details
Main Authors: Irene Gallo, Lorenza Rattazzi, Giuseppa Piras, Thomas Gobbetti, Elisabetta Panza, Mauro Perretti, Jeffrey W Dalley, Fulvio D'Acquisto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4269406?pdf=render