SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM

SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM

Background and Purpose: Mitochondrial dysfunction remains the crucial cause for many heart diseases including diabetic cardiomyopathy (DCM). Sirtuin-3 (SIRT-3) is a protein deacetylase localized in the mitochondria and regulates mitochondrial function. Being a noteworthy mitochondrial protein deacet...

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Bibliographic Details
Main Authors: Pankaj K. Bagul, Parmeshwar B. Katare, Paramesha Bugga, Amit K. Dinda, Sanjay K. Banerjee
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Cells
Subjects:
diabetic cardiomyopathy
transcription factor A
mitochondria
acetylation
Online Access:https://www.mdpi.com/2073-4409/7/12/235

Internet

https://www.mdpi.com/2073-4409/7/12/235

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