Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank

Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank

Here, the authors design a multiplex serology platform to quantitatively measure antibodies against 20 infectious agents in UK Biobank participants and confirm associations of antibody responses with sociodemographic characteristics, HLA genetic variants, and disease outcomes.

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Hlavní autoři: Alexander J. Mentzer, Nicole Brenner, Naomi Allen, Thomas J. Littlejohns, Amanda Y. Chong, Adrian Cortes, Rachael Almond, Michael Hill, Simon Sheard, Gil McVean, UKB Infection Advisory Board, Rory Collins, Adrian V. S. Hill, Tim Waterboer
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2022-04-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-022-29307-3

Internet

https://doi.org/10.1038/s41467-022-29307-3

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