Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank

Identification of host–pathogen-disease relationships using a scalable multiplex serology platform in UK Biobank

Here, the authors design a multiplex serology platform to quantitatively measure antibodies against 20 infectious agents in UK Biobank participants and confirm associations of antibody responses with sociodemographic characteristics, HLA genetic variants, and disease outcomes.

Bibliographic Details
Main Authors: Alexander J. Mentzer, Nicole Brenner, Naomi Allen, Thomas J. Littlejohns, Amanda Y. Chong, Adrian Cortes, Rachael Almond, Michael Hill, Simon Sheard, Gil McVean, UKB Infection Advisory Board, Rory Collins, Adrian V. S. Hill, Tim Waterboer
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29307-3

Internet

https://doi.org/10.1038/s41467-022-29307-3

Similar Items