Endothelial Cell GATA2 Modulates the Cardiomyocyte Stress Response through the Regulation of Two Long Non-Coding RNAs

Endothelial Cell GATA2 Modulates the Cardiomyocyte Stress Response through the Regulation of Two Long Non-Coding RNAs

Capillary endothelial cells modulate myocardial growth and function during pathological stress, but it is unknown how and whether this contributes to the development of heart failure. We found that the endothelial cell transcription factor GATA2 is downregulated in human failing myocardium. Endothel...

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Bibliographic Details
Main Authors: Natali Froese, Malgorzata Szaroszyk, Mortimer Korf-Klingebiel, Katrin Koch, Jan D. Schmitto, Robert Geffers, Denise Hilfiker-Kleiner, Christian Riehle, Kai C. Wollert, Johann Bauersachs, Joerg Heineke
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biology
Subjects:
pressure overload
cardiac endothelial cells
paracrine signaling
Online Access:https://www.mdpi.com/2079-7737/11/12/1736

Internet

https://www.mdpi.com/2079-7737/11/12/1736

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