Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats

Botulinum neurotoxins (BoNT) are potential biothreat agents due to their high lethality, potency, and ease of distribution, thus the development of antitoxins is a high priority to the US government. This study examined pre-clinical pharmacokinetic studies in rats of four oligoclonal anti-BoNT mAb-b...

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Bibliographic Details
Main Authors: Yero Espinoza, David Wong, Ago Ahene, Kenneth Der, Zachary Martinez, John Pham, Ronald R. Cobb, Shauna Farr-Jones, James. D. Marks, Milan T. Tomic
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/11/6/345