Oridonin Delays Aging Through the AKT Signaling Pathway

Oridonin Delays Aging Through the AKT Signaling Pathway

Aging is a major risk factor for chronic diseases and disability in humans. Nowadays, no effective anti-aging treatment is available clinically. In this study, oridonin was selected based on the drug screening strategy similar to Connectivity MAP (CMAP) but upon transcriptomes of 102 traditional Chi...

Full description

Bibliographic Details
Main Authors: Yongpan An, Jie Zhu, Xin Wang, Xinpei Sun, Chunxiong Luo, Yukun Zhang, Yuwei Ye, Xiaowei Li, Abudumijiti Abulizi, Zhizhen Huang, Hang Zhang, Baoxue Yang, Zhengwei Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
oridonin
anti-aging
Akt
cell senescence
yeast
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.888247/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.888247/full

Similar Items